Head to Head
| NCAAF | 2009/11/07 12:00 | West Virginia v Louisville | L | 17-9 |
| NCAAF | 2008/11/22 12:00 | Louisville v West Virginia | L | 21-35 |
| NCAAF | 2007/11/08 12:00 | West Virginia v Louisville | L | 38-31 |
| NCAAF | 2006/11/02 12:00 | Louisville v West Virginia | W | 44-34 |
| NCAAF | 2005/10/15 12:00 | West Virginia v Louisville | L | 46-44 |
Home History
| NCAAF | 2010/11/13 12:00 | Louisville v South Florida | L | 21-24 |
| NCAAF | 2010/11/06 12:00 | Syracuse v Louisville | W | 20-28 |
| NCAAF | 2010/10/30 12:00 | Pittsburgh v Louisville | L | 20-3 |
| NCAAF | 2010/10/23 12:00 | Louisville v Connecticut | W | 26-0 |
| NCAAF | 2010/10/15 12:00 | Louisville v Cincinnati | L | 27-35 |
| NCAAF | 2010/10/09 12:00 | Louisville v Memphis | W | 56-0 |
| NCAAF | 2010/10/02 12:00 | Arkansas State v Louisville | W | 24-34 |
| NCAAF | 2010/09/18 12:00 | Oregon State v Louisville | L | 35-28 |
Away History
| NCAAF | 2010/11/13 12:00 | West Virginia v Cincinnati | W | 37-10 |
| NCAAF | 2010/10/29 12:00 | Connecticut v West Virginia | L | 16-13 |
| NCAAF | 2010/10/23 12:00 | West Virginia v Syracuse | L | 14-19 |
| NCAAF | 2010/10/14 12:00 | West Virginia v South Florida | W | 20-6 |
| NCAAF | 2010/10/09 12:00 | West Virginia v UNLV | W | 49-10 |
| NCAAF | 2010/09/25 12:00 | LSU v West Virginia | L | 20-14 |
| NCAAF | 2010/09/18 12:00 | West Virginia v Maryland | W | 31-17 |
| NCAAF | 2010/09/10 12:00 | Marshall v West Virginia | W | 21-24 |