Head to Head
| ATP - Montreal | 2015/08/13 20:35 | Nick Kyrgios v John Isner | 5-7,3-6 |
| ATP - Madrid | 2015/05/07 12:50 | Nick Kyrgios v John Isner | 3-6,7-6,4-6 |
Home History
| ATP - Miami | 2017/03/31 23:00 | Nick Kyrgios v Roger Federer | 6-7,7-6,6-7 |
| ATP - Miami | 2017/03/30 23:00 | Alexander Zverev v Nick Kyrgios | 4-6,7-6,3-6 |
| ATP - Miami | 2017/03/29 01:45 | Nick Kyrgios v David Goffin | 7-6,6-3 |
| ATP - Miami | 2017/03/27 20:15 | Nick Kyrgios v Ivo Karlovič | 6-4,6-7,7-6 |
| ATP - Miami | 2017/03/26 02:20 | Nick Kyrgios v Damir Dzumhur | 6-4,6-3 |
| ATP - Indian Wells | 2017/03/15 22:00 | Nick Kyrgios v Novak Djokovič | 6-4,7-6 |
| ATP - Indian Wells | 2017/03/14 22:30 | Nick Kyrgios v Alexander Zverev | 6-3,6-4 |
| ATP - Indian Wells | 2017/03/12 23:10 | Nick Kyrgios v Horacio Zeballos | 6-3,6-4 |
Away History
| ATP - Miami | 2017/03/27 20:40 | John Isner v Alexander Zverev | 7-6,6-7,6-7 |
| ATP - Miami | 2017/03/25 18:40 | John Isner v Thomaz Bellucci | 7-5,7-6 |
| ATP - Indian Wells | 2017/03/14 03:30 | Gael Monfils v John Isner | 6-2,6-4 |
| ATP - Indian Wells | 2017/03/11 20:35 | Mikhail Kukushkin v John Isner | 6-7,6-7 |
| ATP - Acapulco | 2017/02/28 00:00 | John Isner v Steve Johnson | 4-6,4-6 |
| ATP Memphis | 2017/02/18 01:30 | Donald Young v John Isner | 7-6,3-6,7-6 |
| ATP Memphis | 2017/02/16 01:30 | Yoshihito Nishioka v John Isner | 6-4,3-6,4-6 |
| Davis Cup | 2017/02/03 23:15 | John Isner v Henri Laaksonen | 4-6,6-2,6-2,7-6 |