[12] NJ Devils 4-3 BUF Sabres [6] 2021-12-30 00:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Lindy Ruff
Head to Head
| NHL | 2021/10/23 23:00 | BUF Sabres v NJ Devils | W | 1-2 |
| NHL | 2021/04/08 23:00 | NJ Devils v BUF Sabres | W | 6-3 |
| NHL | 2021/04/06 23:00 | BUF Sabres v NJ Devils | L | 5-3 |
| NHL | 2021/03/16 23:00 | BUF Sabres v NJ Devils | W | 2-3 |
| NHL | 2021/02/26 00:00 | NJ Devils v BUF Sabres | W | 4-3 |
| NHL | 2021/02/24 00:00 | BUF Sabres v NJ Devils | L | 4-1 |
| NHL | 2021/02/20 17:30 | BUF Sabres v NJ Devils | L | 3-2 |
| NHL | 2021/01/31 18:00 | NJ Devils v BUF Sabres | W | 5-3 |
Home History
| NHL | 2021/12/20 00:00 | PIT Penguins v NJ Devils | L | 3-2 |
| NHL | 2021/12/19 01:00 | NJ Devils v DET Red Wings | L | 2-5 |
| NHL | 2021/12/17 00:00 | VGS Golden Knights v NJ Devils | L | 5-3 |
| NHL | 2021/12/15 00:00 | NJ Devils v PHI Flyers | L | 1-6 |
| NHL | 2021/12/12 00:30 | NJ Devils v NY Islanders | L | 2-4 |
| NHL | 2021/12/11 00:30 | NAS Predators v NJ Devils | L | 3-2 |
| NHL | 2021/12/09 00:00 | PHI Flyers v NJ Devils | W | 0-3 |
| NHL | 2021/12/07 00:00 | OTT Senators v NJ Devils | L | 3-2 |
Away History
| NHL | 2021/12/18 00:00 | BUF Sabres v PIT Penguins | L | 2-3 |
| NHL | 2021/12/17 01:00 | BUF Sabres v MIN Wild | W | 3-2 |
| NHL | 2021/12/15 01:00 | BUF Sabres v WIN Jets | W | 4-2 |
| NHL | 2021/12/12 00:00 | WAS Capitals v BUF Sabres | L | 3-2 |
| NHL | 2021/12/11 00:00 | NY Rangers v BUF Sabres | L | 2-1 |
| NHL | 2021/12/08 00:30 | ANA Ducks v BUF Sabres | L | 2-0 |
| NHL | 2021/12/05 00:30 | BUF Sabres v CAR Hurricanes | L | 2-6 |
| NHL | 2021/12/03 00:00 | BUF Sabres v FLA Panthers | L | 4-7 |