[12] Sliema Wanderers 1-1 St Lucia [11] 2022-02-13 15:00
Stadium: Ta' Qali National Stadium Round: 18
Home Manager: Andrea Pisanu Away Manager: Oliver Spiteri
Head to Head
| Malta - Premier League | 2021/10/24 13:00 | Santa Lucia FC v Sliema Wanderers | D | 0-0 |
| Malta - Premier League | 2021/01/29 20:00 | Santa Lucia FC v Sliema Wanderers | W | 0-1 |
| Malta - Premier League | 2020/10/01 19:15 | Sliema Wanderers v Santa Lucia FC | W | 3-1 |
| Malta FA Trophy | 2019/12/01 13:00 | Sliema Wanderers v Santa Lucia FC | L | 0-2 |
| Malta - Premier League | 2019/11/23 13:00 | Santa Lucia FC v Sliema Wanderers | W | 0-4 |
Home History
| Malta FA Trophy | 2022/02/10 14:00 | Sliema Wanderers v Vittoriosa Stars | W | 3-0 |
| Malta - Premier League | 2022/02/05 17:00 | Hibernians v Sliema Wanderers | L | 1-0 |
| Malta - Premier League | 2022/01/29 15:00 | Sliema Wanderers v Sirens | W | 1-0 |
| Malta - Premier League | 2022/01/26 18:00 | Sliema Wanderers v Balzan FC | W | 1-0 |
| Malta - Premier League | 2022/01/22 17:00 | Gudja United v Sliema Wanderers | L | 1-0 |
| Malta - Premier League | 2022/01/18 16:00 | Sliema Wanderers v Gzira United | L | 1-3 |
| Malta - Premier League | 2021/12/19 13:00 | Floriana v Sliema Wanderers | L | 2-0 |
| Malta - Premier League | 2021/12/05 10:30 | Sliema Wanderers v Hamrun Spartans | L | 0-2 |
Away History
| Malta FA Trophy | 2022/02/10 18:00 | Santa Lucia FC v Sirens | W | 4-1 |
| Malta - Premier League | 2022/02/05 13:00 | Mosta FC v Santa Lucia FC | L | 1-0 |
| Malta - Premier League | 2022/01/29 13:00 | Santa Lucia FC v Hibernians | D | 0-0 |
| Malta - Premier League | 2022/01/23 15:00 | Sirens v Santa Lucia FC | L | 2-1 |
| Malta - Premier League | 2022/01/19 16:00 | Santa Lucia FC v Gudja United | L | 0-3 |
| Malta - Premier League | 2021/12/18 13:00 | Gzira United v Santa Lucia FC | D | 2-2 |
| Malta - Premier League | 2021/12/11 13:00 | Santa Lucia FC v Floriana | L | 1-3 |
| Malta - Premier League | 2021/12/05 17:00 | Santa Lucia FC v Balzan FC | D | 3-3 |