[10] St Lucia 0-3 Gudja United [9] 2022-01-19 16:00
Stadium: Luxol Sports Ground Round: 14
Home Manager: Oliver Spiteri Away Manager: Josef Mansueto
Head to Head
| Malta - Premier League | 2021/09/12 19:00 | Gudja United v Santa Lucia FC | D | 2-2 |
| Malta - Premier League | 2020/12/20 16:15 | Santa Lucia FC v Gudja United | W | 3-2 |
| Malta - Premier League | 2020/02/01 15:15 | Santa Lucia FC v Gudja United | W | 2-1 |
| Malta - Premier League | 2019/09/15 16:00 | Gudja United v Santa Lucia FC | D | 1-1 |
| Malta - Challenge League | 2019/04/03 18:15 | Santa Lucia FC v Gudja United | D | 2-2 |
| Malta - 1. divízia | 2018/11/25 14:15 | Gudja United v Santa Lucia FC | D | 1-1 |
Home History
| Malta - Premier League | 2021/12/18 13:00 | Gzira United v Santa Lucia FC | D | 2-2 |
| Malta - Premier League | 2021/12/11 13:00 | Santa Lucia FC v Floriana | L | 1-3 |
| Malta - Premier League | 2021/12/05 17:00 | Santa Lucia FC v Balzan FC | D | 3-3 |
| Malta - Premier League | 2021/11/28 15:00 | Hamrun Spartans v Santa Lucia FC | L | 3-0 |
| Malta - Premier League | 2021/11/21 10:30 | Santa Lucia FC v Birkirkara | W | 2-0 |
| Malta - Premier League | 2021/10/30 15:00 | Valletta v Santa Lucia FC | L | 5-3 |
| Malta - Premier League | 2021/10/24 13:00 | Santa Lucia FC v Sliema Wanderers | D | 0-0 |
| Malta - Premier League | 2021/10/17 17:00 | Santa Lucia FC v Mosta FC | D | 2-2 |
Away History
| Malta - Premier League | 2021/12/19 10:30 | Gudja United v Hibernians | L | 1-2 |
| Malta - Premier League | 2021/12/13 13:00 | Sirens v Gudja United | D | 0-0 |
| Malta - Premier League | 2021/12/04 13:00 | Mosta FC v Gudja United | W | 0-3 |
| Malta - Premier League | 2021/11/28 13:00 | Gzira United v Gudja United | L | 3-2 |
| Malta - Premier League | 2021/11/20 17:00 | Gudja United v Floriana | L | 0-1 |
| Malta - Premier League | 2021/10/31 14:00 | Balzan FC v Gudja United | L | 1-0 |
| Malta - Premier League | 2021/10/23 13:00 | Gudja United v Hamrun Spartans | L | 1-3 |
| Malta - Premier League | 2021/10/16 17:00 | Birkirkara v Gudja United | L | 2-0 |