Stadium: Burke-Tarr Stadium Round: 1
| NCAAF | 2022/11/12 18:00 | Catawba Indians v Carson–Newman Eagles | W | 23-61 |
| NCAAF | 2022/11/05 19:00 | Carson–Newman Eagles v Virginia Wise Highland Cavaliers | W | 38-22 |
| NCAAF | 2022/10/29 17:00 | Emory And Henry Wasps v Carson–Newman Eagles | W | 7-21 |
| NCAAF | 2022/10/22 17:00 | Mars Hill Lions v Carson–Newman Eagles | L | 44-13 |
| NCAAF | 2022/10/15 22:00 | Carson–Newman Eagles v Erskine Flying Fleet | W | 37-0 |
| NCAAF | 2022/10/08 17:30 | Tusculum Pioneers v Carson–Newman Eagles | L | 34-6 |
| NCAAF | 2022/10/01 17:00 | Carson–Newman Eagles v Newberry Wolves | W | 24-14 |
| NCAAF | 2022/09/24 22:00 | Lenoir Rhyne Bears v Carson–Newman Eagles | L | 34-13 |
| NCAAF | 2022/11/12 19:00 | The Citadel v Lynchburg Dragons | L | 66-0 |
| NCAAF | 2022/10/22 21:00 | Southern v Lynchburg Dragons | L | 51-7 |
| NCAAF | 2022/10/15 17:30 | South Carolina State v Lynchburg Dragons | L | 36-0 |
| NCAAF | 2022/10/08 19:00 | Savannah State v Lynchburg Dragons | L | 28-14 |
| NCAAF | 2022/10/01 16:00 | Morgan State v Lynchburg Dragons | L | 44-10 |
| NCAAF | 2022/09/24 20:00 | North Carolina Central v Lynchburg Dragons | L | 59-14 |
| NCAAF | 2022/09/17 18:00 | Delaware State v Lynchburg Dragons | L | 35-19 |
| NCAAF | 2022/09/10 17:00 | Presbyterian v Lynchburg Dragons | L | 21-13 |