[8] Cerro Largo 0-2 Penarol [7] 2022-10-22 22:00
Stadium: Estadio Arquitecto Antonio Eleuterio Ubilla Round: 15
Referee: Mathias De Armas Home Manager: Mario Saralegui Away Manager: Leonardo Ramos
Head to Head
| Uruguaj - Apertura | 2022/06/04 19:00 | Penarol v Cerro Largo | W | 0-1 |
| Uruguaj - Clausura | 2021/11/23 00:45 | Penarol v Cerro Largo | D | 2-2 |
| Uruguaj - Apertura | 2021/08/06 21:00 | Cerro Largo v Penarol | L | 0-1 |
| Copa Sudamericana | 2021/04/14 00:30 | Penarol v Cerro Largo | L | 4-1 |
| Copa Sudamericana | 2021/04/07 00:30 | Cerro Largo v Penarol | D | 2-2 |
| Uruguaj - Clausura | 2021/02/17 22:30 | Cerro Largo v Penarol | D | 1-1 |
| Uruguaj - Apertura | 2020/08/27 23:15 | Penarol v Cerro Largo | L | 2-0 |
| Uruguaj - Clausura | 2019/12/05 23:30 | Penarol v Cerro Largo | L | 2-1 |
| Uruguaj - Apertura | 2019/06/02 19:00 | Cerro Largo v Penarol | W | 1-0 |