| NCAAF | 11/11 19:00 | 1 | Bridgewater Eagles v Guilford Quakers | L | 47-15 | |
| NCAAF | 11/04 19:00 | 1 |
Guilford Quakers
v
Averett Cougars
|
L | 13-34 | |
| NCAAF | 10/28 17:00 | 1 | Guilford Quakers v Hampden Sydney Tigers | L | 21-42 | |
| NCAAF | 10/21 19:30 | 1 | Ferrum Panthers v Guilford Quakers | L | 28-0 | |
| NCAAF | 10/14 17:00 | 1 | Guilford Quakers v Shenandoah Hornets | L | 20-31 | |
| NCAAF | 10/07 20:00 | 1 | Washington And Lee Generals v Guilford Quakers | L | 48-25 | |
| NCAAF | 09/30 17:00 | 1 | Guilford Quakers v Randolph Macon Yellow Jackets | L | 14-70 | |
| NCAAF | 09/16 18:00 | 1 | Huntingdon Hawks v Guilford Quakers | L | 40-14 | |
| NCAAF | 09/09 22:00 | 1 | Methodist Monarchs v Guilford Quakers | W | 21-39 | |
| NCAAF | 09/02 23:00 | 1 | Guilford Quakers v Greensboro Pride | W | 36-21 | |
| NCAAF | 11/12 18:00 | 1 | Guilford Quakers v Bridgewater Eagles | L | 22-64 | |
| NCAAF | 11/05 17:00 | 1 |
Averett Cougars
v
Guilford Quakers
|
W | 0-26 | |
| NCAAF | 10/29 17:00 | 1 | Hampden Sydney Tigers v Guilford Quakers | L | 28-21 | |
| NCAAF | 10/22 17:00 | 1 | Guilford Quakers v Ferrum Panthers | L | 17-31 | |
| NCAAF | 10/15 17:00 | 1 | Shenandoah Hornets v Guilford Quakers | L | 38-35 | |
| NCAAF | 10/08 18:00 | 1 | Guilford Quakers v Washington And Lee Generals | L | 6-31 | |
| NCAAF | 10/01 17:00 | 1 | Randolph Macon Yellow Jackets v Guilford Quakers | L | 48-19 | |
| NCAAF | 09/17 17:00 | 1 | Guilford Quakers v Huntingdon Hawks | L | 7-47 | |
| NCAAF | 09/10 23:00 | 1 | Guilford Quakers v Methodist Monarchs | L | 16-49 | |
| NCAAF | 09/03 16:00 | 1 | Greensboro Pride v Guilford Quakers | W | 37-48 | |
| NCAAF | 11/13 19:00 | 1 | Bridgewater Eagles v Guilford Quakers | L | 43-0 | |
| NCAAF | 11/06 17:00 | 1 | Guilford Quakers v Emory And Henry Wasps | L | 13-66 | |
| NCAAF | 10/30 18:00 | 1 | Ferrum Panthers v Guilford Quakers | L | 57-35 | |
| NCAAF | 10/16 17:00 | 1 | Guilford Quakers v Randolph Macon Yellow Jackets | L | 0-58 | |
| NCAAF | 10/09 16:00 | 1 | Guilford Quakers v Shenandoah Hornets | L | 25-52 | |
| NCAAF | 09/25 17:00 | 1 | Guilford Quakers v Hampden Sydney Tigers | L | 27-28 | |
| NCAAF | 09/18 17:00 | 1 | Washington And Lee Generals v Guilford Quakers | L | 52-0 | |
| NCAAF | 09/04 23:00 | 1 | Guilford Quakers v Greensboro Pride | W | 21-7 | |
| NCAAF | 11/16 18:00 | 1 | Bridgewater Eagles v Guilford Quakers | L | 41-7 | |
| NCAAF | 11/09 18:00 | 1 | Guilford Quakers v Emory And Henry Wasps | L | 22-38 |